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New research reveals using statins within 14 days of acute coronary syndromes (ACS) does not reduce the risk of heart attack, stroke or death for up to four months. Examples of ACS include heart attack or unstable angina.

Previous research has suggested long-term statin therapy reduces the risk of heart attack, stroke, and death in patients who are at varying risks for cardiovascular disease. However, these studies usually excluded patients with recent ACS. Researchers say the early period after the onset of ACS is a critical time of coronary heart disease with a high risk of recurrent events and death, thus making treatment paramount.

Researchers from the University Hospital Basel, Switzerland, analyzed 12 previous studies to evaluate the early use of statins following ACS.

Results reveal there were no statistically significant risk reductions from early statin therapy for total death, total heart attack, total stroke, cardiovascular death, fatal or nonfatal heart attack or revascularization procedures at one month and four months of follow-up. Researchers add serious adverse effects associated with early initiation of statins are rare.

This article was reported by Ivanhoe.com, who offers Medical Alerts by e-mail every day of the week. To subscribe, go to: http://www.ivanhoe.com/newsalert/.

SOURCE: The Journal of the American Medical Association, 2006;295:2046-2056

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