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An experimental treatment for osteoporosis looks promising after testing in rats.

A professor at New York College of Dentistry has developed a supplement that significantly improves the strength and thickness of bones without the side effects of many current drug treatments. It is a combination of magnesium (Mg), zinc (Zn), and fluoride (F) ions in a calcium-phosphate (CaP) matrix.

A new study shows even a small amount of Mg/Zn/F-CaP substantially improved bone strength and thickness in the femurs of rats. It also shows the supplement does not have the side effects of current osteoporosis medications. Many of them can increase the risk of heart disease, strokes and breast cancer.

Dr. Racquel Z. LeGeros, a Professor of Biomaterials and Biomimetics and of Implant Dentistry developed the supplement. She says it would be inexpensive to produce and would not need approval from the FDA because it would be marketed as an over-the-counter supplement.

LeGeros says more studies on Mg/Zn/F-CaP are needed in humans to confirm this study’s results. She adds future research may focus on using the supplement to repair fractures and periodontal bone defects.

This article was reported by Ivanhoe.com, who offers Medical Alerts by e-mail every day of the week. To subscribe, go to: http://www.ivanhoe.com/newsalert/.

SOURCE: American Association for Dental Research Annual Meeting in Orlando, Fla., March 8-11, 2006

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