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Green noted that a previous study using the same UK database had found no link between bisphosphonates and esophageal cancer, but said her research had tracked patients for almost twice as long. She also said that with populations aging, bone diseases such as osteoporosis were becoming more common, leading to higher levels of bisphosphonate use.

"It's important to see our findings as part of a wider picture. These are very commonly prescribed drugs and we don't have enough information about the long-term risks and benefits."