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Medical Services | Health Information | Appointments | Education and Research | Jobs | About Rapid-onset Alzheimer's: Could it be something else?

My mother has been diagnosed with Alzheimer's disease. But she seems to be deteriorating at a very rapid rate. Everything I've read about Alzheimer's says that it has a slow progression. What can you tell me about this?
- No name / No state given
Mayo Clinic neuropsychologist Glenn Smith, Ph.D., and colleagues answer select questions from readers.
Answer
Alzheimer's is a degenerative disease, which usually implies a slow progression. However, rarely Alzheimer's can progress more rapidly — over weeks or months instead of years.

A rapid progression may also suggest that a second type of dementia is complicating the Alzheimer's — such as vascular dementia or Lewy body disease. In addition, rapid progression may indicate another condition that mimics the symptoms of Alzheimer's, such as:

Infections that affect the central nervous system, such as HIV and Creutzfeldt-Jakob disease
A side effect of certain medications, such as anticholinergic drugs and narcotic pain relievers
Vitamin B-12 deficiency
Depression
Hypothyroidism
A prompt and thorough medical evaluation is important to determine the exact cause of rapidly progressing dementia. Some causes are treatable.

MORE ON THIS TOPIC
Alzheimer's or depression: Could it be both?
Vitamin B-12: Can it improve memory in Alzheimer's?
Dementia: It's not always Alzheimer's
Hypothyroidism (underactive thyroid gland)

RELATED
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'Mayo Clinic Guide to Alzheimer's Disease' (Hardcover)
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Oct 11, 2007
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